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Crystal Structure of the Yeast Inner Kinetochore Subunit Cep3p

In budding yeast, the four-protein CBF3 complex (Skp1p-Ctf13p-Cep3p-Ndc10p) initiates kinetochore assembly by binding to the CDEIII locus of centromeric DNA. A Cep3p dimer recruits a Ctf13p-Skp1p heterodimer and contacts two sites on CDEIII. We report here the crystal structure, determined at 2.8 Å...

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Autors principals: Bellizzi, John J., Sorger, Peter K., Harrison, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288795/
https://ncbi.nlm.nih.gov/pubmed/17997968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.09.008
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