Llwytho...

Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance

The emergence of multi-resistant pathogenic bacteria is a worldwide health issue. Recently, clinical variants of a single antibiotic-modifying acetyltransferase, AAC(6′)-Ib—a variant of aminoglycoside 6′-N-acetyltransferase—have been identified that confer extended resistance to most aminoglycosides...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maurice, Frédérique, Broutin, Isabelle, Podglajen, Isabelle, Benas, Philippe, Collatz, Ekkehard, Dardel, Frédéric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288771/
https://ncbi.nlm.nih.gov/pubmed/18292754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.9
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