A functional TNFRSF5 gene variant is associated with risk of lymphoma

CD40 and its ligand, CD154, are major costimulatory molecules whose interactions are important in humoral and cellular immunity. We hypothesized that single nucleotide polymorphisms (SNPs) in TNFRSF5 and TNFSF5 encoding the CD40 and CD154 proteins, respectively, influence lymphoma risk, particularly...

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Main Authors: Skibola, Christine F., Nieters, Alexandra, Bracci, Paige M., Curry, John D., Agana, Luz, Skibola, Danica R., Hubbard, Alan, Becker, Nikolaus, Smith, Martyn T., Holly, Elizabeth A.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2008
主題:
Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288730/
https://ncbi.nlm.nih.gov/pubmed/18287517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-112144
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