A functional TNFRSF5 gene variant is associated with risk of lymphoma

CD40 and its ligand, CD154, are major costimulatory molecules whose interactions are important in humoral and cellular immunity. We hypothesized that single nucleotide polymorphisms (SNPs) in TNFRSF5 and TNFSF5 encoding the CD40 and CD154 proteins, respectively, influence lymphoma risk, particularly...

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Detalhes bibliográficos
Main Authors: Skibola, Christine F., Nieters, Alexandra, Bracci, Paige M., Curry, John D., Agana, Luz, Skibola, Danica R., Hubbard, Alan, Becker, Nikolaus, Smith, Martyn T., Holly, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288730/
https://ncbi.nlm.nih.gov/pubmed/18287517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-112144
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