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Methods for Kinetic and Thermodynamic Analysis of Aminoacyl-tRNA Synthetases

The accuracy of protein synthesis relies on the ability of aminoacyl-tRNA synthetases (aaRSs) to discriminate among true and near cognate substrates. To date, analysis of aaRSs function, including identification of residues of aaRS participating in amino acid and tRNA discrimination, has largely rel...

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Détails bibliographiques
Auteurs principaux: Francklyn, Christopher S., First, Eric A., Perona, John J., Hou, Ya-Ming
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288706/
https://ncbi.nlm.nih.gov/pubmed/18241792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2007.09.007
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