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Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of a Novel Histone Deacetylase Inhibitor, LAQ824, in Human Colon Carcinoma Cells and Xenografts

The aim of this work was to use phosphorus magnetic resonance spectroscopy ((31)P MRS) to investigate the pharmacodynamic effects of LAQ824, a histone deacetylase (HDAC) inhibitor. Human HT29 colon carcinoma cells were examined by (31)P MRS after treatment with LAQ824 and another HDAC inhibitor, sub...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chung, Yuen-Li, Troy, Helen, Kristeleit, Rebecca, Aherne, Wynne, Jackson, L Elizabeth, Atadja, Peter, Griffiths, John R, Judson, Ian R, Workman, Paul, Leach, Martin O, Beloueche-Babari, Mounia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press Inc. 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288545/
https://ncbi.nlm.nih.gov/pubmed/18392140
Tagiau: Ychwanegu Tag
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