A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy

Tumor targeting peptides are promising vehicles for site-directed cancer therapy. Pep42, a cyclic 13-mer oligopeptide that specifically binds to glucose-regulated protein 78 (GRP78) and internalized into cancer cells, represents an excellent vehicle for tumor cell-specific chemotherapy. Here, we rep...

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Bibliographic Details
Main Authors: Yoneda, Yoshiyuki, Steiniger, Sebastian C.J., Čapková, Kateřina, Mee, Jenny M., Liu, Ying, Kaufmann, Gunnar F., Janda, Kim D.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288489/
https://ncbi.nlm.nih.gov/pubmed/18243696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.01.060
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