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Specific recognition of a dsDNA sequence motif by an immunoglobulin V(H) homodimer

Anti-DNA antibodies have the potential to be applied in vast fields of fundamental as well as medical research. They are found in autoimmune diseases, such as systemic lupus erythemotosus. In most cases, anti-dsDNA antibodies do not present sequence specificity and are of low affinity. The dominant...

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Detalhes bibliográficos
Main Authors: Jin, Hulin, Sepúlveda, Jorge, Burrone, Oscar R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2287315/
https://ncbi.nlm.nih.gov/pubmed/15557264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04921704
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