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Use of the lambda Red recombinase system to rapidly generate mutants in Pseudomonas aeruginosa

BACKGROUND: The Red recombinase system of bacteriophage lambda has been used to inactivate chromosomal genes in various bacteria and fungi. The procedure consists of electroporating a polymerase chain reaction (PCR) fragment that was obtained with a 1- or 3-step PCR protocol and that carries an anti...

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Autori principali: Lesic, Biliana, Rahme, Laurence G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2287187/
https://ncbi.nlm.nih.gov/pubmed/18248677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-20
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