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Stabilization of discordant helices in amyloid fibril-forming proteins

Several proteins and peptides that can convert from α-helical to β-sheet conformation and form amyloid fibrils, including the amyloid β-peptide (Aβ) and the prion protein, contain a discordant α-helix that is composed of residues that strongly favor β-strand formation. In their native states, 37 of...

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Sonraí Bibleagrafaíochta
Main Authors: Päiviö, Anna, Nordling, Erik, Kallberg, Yvonne, Thyberg, Johan, Johansson, Jan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286751/
https://ncbi.nlm.nih.gov/pubmed/15096631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03442404
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