Distinct conformational stability and functional activity of four highly homologous endonuclease colicins

The family of conserved colicin DNases E2, E7, E8, and E9 are microbial toxins that kill bacteria through random degradation of the chromosomal DNA. In the present work, we compare side by side the conformational stabilities of these four highly homologous colicin DNases. Our results indicate that t...

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Main Authors: van den Bremer, Ewald T.J., Keeble, Anthony H., Jiskoot, Wim, Spelbrink, Robin E.J., Maier, Claudia S., Van Hoek, Arie, Visser, Antonie J.W.G., James, Richard, Moore, Geoffrey R., Kleanthous, Colin, Heck, Albert J.R.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286750/
https://ncbi.nlm.nih.gov/pubmed/15096639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03508204
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