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Direct Activation of Cyclin-Dependent Kinase 2 by Human Papillomavirus E7
Addition of human papillomavirus (HPV) E7 CDK2/cyclin A or CDK2/cyclin E, purified from either insect cells or bacteria, dramatically upregulates histone H1 kinase activity. Activation is substrate specific, with a smaller effect noted for retinoblastoma protein (Rb). The CDK2 stimulatory activity i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC228519/ https://ncbi.nlm.nih.gov/pubmed/12970441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.19.10566-10574.2003 |
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