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Cellular Immunity Elicited by Human Immunodeficiency Virus Type 1/ Simian Immunodeficiency Virus DNA Vaccination Does Not Augment the Sterile Protection Afforded by Passive Infusion of Neutralizing Antibodies

High levels of infused anti-human immunodeficiency virus type 1 (HIV-1) neutralizing monoclonal antibodies (MAbs) can completely protect macaque monkeys against mucosal chimeric simian-human immunodeficiency virus (SHIV) infection. Antibody levels below the protective threshold do not prevent infect...

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Published in:J Virol
Main Authors: Mascola, John R., Lewis, Mark G., VanCott, Thomas C., Stiegler, Gabriela, Katinger, Hermann, Seaman, Michael, Beaudry, Kristin, Barouch, Dan H., Korioth-Schmitz, Birgit, Krivulka, Georgia, Sambor, Anna, Welcher, Brent, Douek, Daniel C., Montefiori, David C., Shiver, John W., Poignard, Pascal, Burton, Dennis R., Letvin, Norman L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2003
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC228504/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12970419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.19.10348-10356.2003
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