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Enhanced Virulence Mediated by the Murine Coronavirus, Mouse Hepatitis Virus Strain JHM, Is Associated with a Glycine at Residue 310 of the Spike Glycoprotein

The coronavirus, mouse hepatitis virus strain JHM, causes acute and chronic neurological diseases in rodents. Here we demonstrate that two closely related virus variants, both of which cause acute encephalitis in susceptible strains of mice, cause markedly different diseases if mice are protected wi...

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Bibliografiske detaljer
Main Authors: Ontiveros, Evelena, Kim, Taeg S., Gallagher, Thomas M., Perlman, Stanley
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC228498/
https://ncbi.nlm.nih.gov/pubmed/12970410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.19.10260-10269.2003
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