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Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

Traditional treatment of infectious diseases is based on compounds that aim to kill or inhibit bacterial growth. A major concern with this approach is the frequently observed development of resistance to antimicrobial compounds. The discovery of bacterial-communication systems (quorum-sensing system...

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Détails bibliographiques
Auteurs principaux: Hentzer, Morten, Givskov, Michael
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC228474/
https://ncbi.nlm.nih.gov/pubmed/14597754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200320074
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