The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations
The Saccharomyces cerevisiae genome encodes four MutL homologs. Of these, MLH1 and PMS1 are known to act in the MSH2-dependent pathway that repairs DNA mismatches. We have investigated the role of MLH3 in mismatch repair. Mutations in MLH3 increased the rate of reversion of the hom3–10 allele by inc...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12404 |
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