The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations
The Saccharomyces cerevisiae genome encodes four MutL homologs. Of these, MLH1 and PMS1 are known to act in the MSH2-dependent pathway that repairs DNA mismatches. We have investigated the role of MLH3 in mismatch repair. Mutations in MLH3 increased the rate of reversion of the hom3–10 allele by inc...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12404 |
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