Nalaganje...

The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations

The Saccharomyces cerevisiae genome encodes four MutL homologs. Of these, MLH1 and PMS1 are known to act in the MSH2-dependent pathway that repairs DNA mismatches. We have investigated the role of MLH3 in mismatch repair. Mutations in MLH3 increased the rate of reversion of the hom3–10 allele by inc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Flores-Rozas, Hernan, Kolodner, Richard D.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC22844/
https://ncbi.nlm.nih.gov/pubmed/9770499
Oznake: Označite
Brez oznak, prvi označite!