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Identification of the binding site for Gqα on its effector Bruton’s tyrosine kinase
Heterotrimeric G proteins and tyrosine kinases are two major cellular signal transducers. Although G proteins are known to activate tyrosine kinases, the activation mechanism is not clear. Here, we demonstrate that G protein Gqα binds directly to the nonreceptor Bruton’s tyrosine kinase (Btk) to a r...
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Main Authors: | , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The National Academy of Sciences
1998
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22808/ https://ncbi.nlm.nih.gov/pubmed/9770463 |
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