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Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements
The variation in inhibitor specificity for five different amine inhibitors bound to CST, BT, and the cold-adapted AST has been studied by use of association constant measurements, structural analysis of high-resolution crystal structures, and the LIE method. Experimental data show that AST binds the...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2280040/ https://ncbi.nlm.nih.gov/pubmed/15044735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03498604 |
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