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Trypsin specificity as elucidated by LIE calculations, X-ray structures, and association constant measurements

The variation in inhibitor specificity for five different amine inhibitors bound to CST, BT, and the cold-adapted AST has been studied by use of association constant measurements, structural analysis of high-resolution crystal structures, and the LIE method. Experimental data show that AST binds the...

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Detaylı Bibliyografya
Asıl Yazarlar: Leiros, Hanna-Kirsti Schrøder, Brandsdal, Bjørn Olav, Andersen, Ole Andreas, Os, Vibeke, Leiros, Ingar, Helland, Ronny, Otlewski, Jacek, Willassen, Nils Peder, Smalås, Arne O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2280040/
https://ncbi.nlm.nih.gov/pubmed/15044735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03498604
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