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Long-range allosteric transitions in carbamoyl phosphate synthetase

Carbamoyl phosphate synthetase plays a key role in both pyrimidine and arginine biosynthesis by catalyzing the production of carbamoyl phosphate from one molecule of bicarbonate, two molecules of MgATP, and one molecule of glutamine. The enzyme from Escherichia coli consists of two polypeptide chain...

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Bibliographic Details
Main Authors: Thoden, James B., Huang, Xinyi, Kim, Jungwook, Raushel, Frank M., Holden, Hazel M.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2280008/
https://ncbi.nlm.nih.gov/pubmed/15322282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04822704
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