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Replacement of proline with valine does not remove an apparent proline isomerization-dependent folding event in CRABP I
Site-directed mutagenesis has frequently been used to replace proline with other amino acids in order to determine if proline isomerization is responsible for a slow phase during refolding. Replacement of Pro 85 with alanine in cellular retinoic acid binding protein I (CRABP-I) abolished the slowest...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279983/ https://ncbi.nlm.nih.gov/pubmed/15152096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03317804 |
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