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Experimentally biased model structure of the Hsc70/auxilin complex: Substrate transfer and interdomain structural change

A model structure of the Hsc70/auxilin complex has been constructed to gain insight into interprotein substrate transfer and ATP hydrolysis induced conformational changes in the multidomain Hsc70 structure. The Hsc70/auxilin system, which is a member of the Hsp70/Hsp40 chaperone system family, uncoa...

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Detalhes bibliográficos
Main Authors: Gruschus, James M., Greene, Lois E., Eisenberg, Evan, Ferretti, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279835/
https://ncbi.nlm.nih.gov/pubmed/15273304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03390504
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