Strain-Specific Virulence Phenotypes of Streptococcus pneumoniae Assessed Using the Chinchilla laniger Model of Otitis Media

BACKGROUND: Streptococcus pneumoniae [Sp] infection is associated with local and systemic disease. Our current understanding of the differential contributions of genetic strain variation, serotype, and host response to disease phenotype is incomplete. Using the chinchilla model of otitis media [OM]...

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Hauptverfasser: Forbes, Michael L., Horsey, Edward, Hiller, N. Luisa, Buchinsky, Farrel J., Hayes, Jay D., Compliment, James M., Hillman, Todd, Ezzo, Suzanne, Shen, Kai, Keefe, Randy, Barbadora, Karen, Post, J. Christopher, Hu, Fen Ze, Ehrlich, Garth D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279396/
https://ncbi.nlm.nih.gov/pubmed/18398481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001969
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