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Strain-Specific Virulence Phenotypes of Streptococcus pneumoniae Assessed Using the Chinchilla laniger Model of Otitis Media

BACKGROUND: Streptococcus pneumoniae [Sp] infection is associated with local and systemic disease. Our current understanding of the differential contributions of genetic strain variation, serotype, and host response to disease phenotype is incomplete. Using the chinchilla model of otitis media [OM]...

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Detalhes bibliográficos
Main Authors: Forbes, Michael L., Horsey, Edward, Hiller, N. Luisa, Buchinsky, Farrel J., Hayes, Jay D., Compliment, James M., Hillman, Todd, Ezzo, Suzanne, Shen, Kai, Keefe, Randy, Barbadora, Karen, Post, J. Christopher, Hu, Fen Ze, Ehrlich, Garth D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279396/
https://ncbi.nlm.nih.gov/pubmed/18398481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001969
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