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Soluble domains of telomerase reverse transcriptase identified by high-throughput screening
Telomerase is a ribonucleoprotein complex responsible for extending the ends of eukaryotic chromosomes. Structural and biophysical studies of this enzyme have been limited by the inability to produce large amounts of recombinant protein. Here we perform a high-throughput screen to map regions of the...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279316/ https://ncbi.nlm.nih.gov/pubmed/16046627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051532105 |
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