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Regulation of Cellular Immortalization and Steady-State Levels of the Telomerase Reverse Transcriptase through Its Carboxy-Terminal Domain

Telomerase maintains cell viability and chromosomal stability through the addition of telomere repeats to chromosome ends. The reactivation of telomerase through the upregulation of TERT, the telomerase protein subunit, is an important step during cancer development, yet TERT protein function and re...

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Detaylı Bibliyografya
Asıl Yazarlar: Middleman, Elaine J., Choi, Jinkuk, Venteicher, Andrew S., Cheung, Peggie, Artandi, Steven E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430280/
https://ncbi.nlm.nih.gov/pubmed/16507993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2146-2159.2006
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