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Regulation of Cellular Immortalization and Steady-State Levels of the Telomerase Reverse Transcriptase through Its Carboxy-Terminal Domain

Telomerase maintains cell viability and chromosomal stability through the addition of telomere repeats to chromosome ends. The reactivation of telomerase through the upregulation of TERT, the telomerase protein subunit, is an important step during cancer development, yet TERT protein function and re...

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Main Authors: Middleman, Elaine J., Choi, Jinkuk, Venteicher, Andrew S., Cheung, Peggie, Artandi, Steven E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430280/
https://ncbi.nlm.nih.gov/pubmed/16507993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2146-2159.2006
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