Beyond PrP(res) Type 1/Type 2 Dichotomy in Creutzfeldt-Jakob Disease

Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently subclassified according to the methionine/valine polymorphism at codon 129 of the PRNP gene and the proteinase K (PK) digested abnormal prion protein (PrP(res)) identified on Western blotting (type 1 or type 2). These biochemically distin...

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Autores principales: Uro-Coste, Emmanuelle, Cassard, Hervé, Simon, Stéphanie, Lugan, Séverine, Bilheude, Jean-Marc, Perret-Liaudet, Armand, Ironside, James W., Haik, Stéphane, Basset-Leobon, Christelle, Lacroux, Caroline, Peoch', Katell, Streichenberger, Nathalie, Langeveld, Jan, Head, Mark W., Grassi, Jacques, Hauw, Jean-Jacques, Schelcher, Francois, Delisle, Marie Bernadette, Andréoletti, Olivier
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279301/
https://ncbi.nlm.nih.gov/pubmed/18389084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000029
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