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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

Cancer progression has similarities with the process of epithelial-to-mesenchymal transition (EMT) found during embryonic development, during which cells down-regulate E-cadherin and up-regulate Vimentin expression. By evaluating the expression of 207 microRNAs (miRNAs) in the 60 cell lines of the d...

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Detalhes bibliográficos
Main Authors: Park, Sun-Mi, Gaur, Arti B., Lengyel, Ernst, Peter, Marcus E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279201/
https://ncbi.nlm.nih.gov/pubmed/18381893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1640608
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