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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
Cancer progression has similarities with the process of epithelial-to-mesenchymal transition (EMT) found during embryonic development, during which cells down-regulate E-cadherin and up-regulate Vimentin expression. By evaluating the expression of 207 microRNAs (miRNAs) in the 60 cell lines of the d...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Cold Spring Harbor Laboratory Press
2008
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279201/ https://ncbi.nlm.nih.gov/pubmed/18381893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1640608 |
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