Potentiation and inhibition of Ca(2+) release-activated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptors

1. The effects of the IP(3)-receptor antagonist 2-aminoethyldiphenyl borate (2-APB) on the Ca(2+) release-activated Ca(2+) current (I(CRAC)) in Jurkat human T cells, DT40 chicken B cells and rat basophilic leukaemia (RBL) cells were examined. 2. 2-APB elicited both stimulatory and inhibitory effects...

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Autores principales: Prakriya, Murali, Lewis, Richard S
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2001
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278849/
https://ncbi.nlm.nih.gov/pubmed/11579153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.t01-1-00003.x
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