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Calmodulin kinase and a calmodulin-binding ‘IQ’ domain facilitate L-type Ca(2+) current in rabbit ventricular myocytes by a common mechanism

1. Ca(2+)–calmodulin-dependent protein kinase II (CaMK) and a calmodulin (CaM)-binding ‘IQ’ domain (IQ) are both implicated in Ca(2+)-dependent regulation of L-type Ca(2+) current (I(Ca)). We used an IQ-mimetic peptide (IQmp), under conditions in which CaMK activity was controlled, to test the relat...

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Detalhes bibliográficos
Main Authors: Wu, Yuejin, Dzhura, Igor, Colbran, Roger J, Anderson, Mark E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278813/
https://ncbi.nlm.nih.gov/pubmed/11559766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.t01-1-00679.x
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