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Free intracellular Mg(2+) concentration and inhibition of NMDA responses in cultured rat neurons

1. Intracellular Mg(2+) (Mg(i)(2+)) blocks single-channel currents and modulates the gating kinetics of NMDA receptors. However, previous data suggested that Mg(i)(2+) inhibits whole-cell current less effectively than predicted from excised-patch measurements. We examined the basis of this discrepan...

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Bibliographic Details
Main Authors: Li-Smerin, Yingying, Levitan, Edwin S, Johnson, Jon W
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278664/
https://ncbi.nlm.nih.gov/pubmed/11410630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.t01-1-00729.x
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