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Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides

How antimicrobial peptides form pores in membranes is of interest as a fundamental membrane process. However, the underlying molecular mechanism, which has potential applications in therapeutics, nonviral gene transfer, and drug delivery, has been in dispute. We have resolved this mechanism by obser...

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Hlavní autoři: Lee, Ming-Tao, Hung, Wei-Chin, Chen, Fang-Yu, Huang, Huey W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278198/
https://ncbi.nlm.nih.gov/pubmed/18375755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710625105
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