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Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides

How antimicrobial peptides form pores in membranes is of interest as a fundamental membrane process. However, the underlying molecular mechanism, which has potential applications in therapeutics, nonviral gene transfer, and drug delivery, has been in dispute. We have resolved this mechanism by obser...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Ming-Tao, Hung, Wei-Chin, Chen, Fang-Yu, Huang, Huey W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278198/
https://ncbi.nlm.nih.gov/pubmed/18375755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710625105
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