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Evidence for Membrane Thinning Effect as the Mechanism for Peptide-Induced Pore Formation

Antimicrobial peptides have two binding states in a lipid bilayer, a surface state S and a pore-forming state I. The transition from the S state to the I state has a sigmoidal peptide-concentration dependence indicating cooperativity in the peptide-membrane interactions. In a previous paper, we repo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Fang-Yu, Lee, Ming-Tao, Huang, Huey W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302957/
https://ncbi.nlm.nih.gov/pubmed/12770881
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