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Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras

Most, if not all, cancers are composed of cells in which more than one gene has a cancer-promoting mutation. Although recent evidence has shown the benefits of therapies targeting a single mutant protein, little attention has been given to situations in which experimental tumors are induced by multi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Podsypanina, Katrina, Politi, Katerina, Beverly, Levi J., Varmus, Harold E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278195/
https://ncbi.nlm.nih.gov/pubmed/18356293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801197105
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