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Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm

A mixture of drugs is often more effective than using a single effector. However, it is extremely challenging to identify potent drug combinations by trial and error because of the large number of possible combinations and the inherent complexity of the underlying biological network. With a closed-l...

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Detalhes bibliográficos
Main Authors: Wong, Pak Kin, Yu, Fuqu, Shahangian, Arash, Cheng, Genhong, Sun, Ren, Ho, Chih-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278193/
https://ncbi.nlm.nih.gov/pubmed/18356295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800823105
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