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Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm
A mixture of drugs is often more effective than using a single effector. However, it is extremely challenging to identify potent drug combinations by trial and error because of the large number of possible combinations and the inherent complexity of the underlying biological network. With a closed-l...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278193/ https://ncbi.nlm.nih.gov/pubmed/18356295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800823105 |
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