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Culturing of human peripheral blood cells reveals unsuspected lymphocyte responses relevant to HIV disease
Recombinant HIV-Tat (Tat) induces extensive apoptosis in peripheral blood mononuclear cells (PBMCs) cultured in typical CO(2) incubators, which are equilibrated with air (21% O(2)). However, as we show here, Tat apoptosis induction fails in PBMCs cultured at physiological oxygen levels (5% O(2)). Un...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278183/ https://ncbi.nlm.nih.gov/pubmed/18364393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712363105 |
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