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Heterozygous Screen in Saccharomyces cerevisiae Identifies Dosage-Sensitive Genes That Affect Chromosome Stability

Current techniques for identifying mutations that convey a small increased cancer risk or those that modify cancer risk in carriers of highly penetrant mutations are limited by the statistical power of epidemiologic studies, which require screening of large populations and candidate genes. To identi...

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Detalhes bibliográficos
Main Authors: Strome, Erin D., Wu, Xiaowei, Kimmel, Marek, Plon, Sharon E.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278055/
https://ncbi.nlm.nih.gov/pubmed/18245329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.084103
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