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Pten deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities
The phosphatidylinositol 3-kinase (PI3K) signaling pathway modulates growth, proliferation and cell survival in diverse tissue types and plays specialized roles in the nervous system including influences on neuronal polarity, dendritic branching and synaptic plasticity. The tumor-suppressor phosphat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278004/ https://ncbi.nlm.nih.gov/pubmed/18082964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.10.048 |
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