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Targeting RNA with cysteine-constrained peptides

A combined approach for targeting RNA with novel, biologically active ligands has been developed using a cyclic peptide library and in silico modeling. This approach has successfully identified novel cyclic peptide constructs that can target bTAR RNA. Subsequently, RNA/peptide interactions were effe...

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Detalhes bibliográficos
Main Authors: Burns, Virginia A., Bobay, Benjamin G., Basso, Anne, Cavanagh, John, Melander, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277476/
https://ncbi.nlm.nih.gov/pubmed/18065222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.11.096
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