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Functional Delivery of siRNA by Disulfide-Constrained Cyclic Amphipathic Peptides

[Image: see text] The promise of oligonucleotide therapeutic agents to perturb expression of disease-related genes remains unrealized, in part due to challenges with functional cellular delivery of these agents. Herein, we describe disulfide-constrained cyclic amphipathic peptides that complex with...

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Bibliografische gegevens
Gepubliceerd in:ACS Med Chem Lett
Hoofdauteurs: Welch, Jade J., Swanekamp, Ria J., King, Christiaan, Dean, David A., Nilsson, Bradley L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2016
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904250/
https://ncbi.nlm.nih.gov/pubmed/27326331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00031
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