An Unbiased Systems Genetics Approach to Mapping Genetic Loci Modulating Susceptibility to Severe Streptococcal Sepsis

Striking individual differences in severity of group A streptococcal (GAS) sepsis have been noted, even among patients infected with the same bacterial strain. We had provided evidence that HLA class II allelic variation contributes significantly to differences in systemic disease severity by modula...

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Hlavní autoři: Abdeltawab, Nourtan F., Aziz, Ramy K., Kansal, Rita, Rowe, Sarah L., Su, Yin, Gardner, Lidia, Brannen, Charity, Nooh, Mohammed M., Attia, Ramy R., Abdelsamed, Hossam A., Taylor, William L., Lu, Lu, Williams, Robert W., Kotb, Malak
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277464/
https://ncbi.nlm.nih.gov/pubmed/18421376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000042
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