An Unbiased Systems Genetics Approach to Mapping Genetic Loci Modulating Susceptibility to Severe Streptococcal Sepsis

Striking individual differences in severity of group A streptococcal (GAS) sepsis have been noted, even among patients infected with the same bacterial strain. We had provided evidence that HLA class II allelic variation contributes significantly to differences in systemic disease severity by modula...

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Main Authors: Abdeltawab, Nourtan F., Aziz, Ramy K., Kansal, Rita, Rowe, Sarah L., Su, Yin, Gardner, Lidia, Brannen, Charity, Nooh, Mohammed M., Attia, Ramy R., Abdelsamed, Hossam A., Taylor, William L., Lu, Lu, Williams, Robert W., Kotb, Malak
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277464/
https://ncbi.nlm.nih.gov/pubmed/18421376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000042
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