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Statistical methodology for the analysis of dye-switch microarray experiments

BACKGROUND: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ensures an automatic correction of the gene-specific labelling bias, it also induces dependencies between log-ratio measurem...

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Autors principals: Mary-Huard, Tristan, Aubert, Julie, Mansouri-Attia, Nadera, Sandra, Olivier, Daudin, Jean-Jacques
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277403/
https://ncbi.nlm.nih.gov/pubmed/18271965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-98
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