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Shape based indexing for faster search of RNA family databases

BACKGROUND: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally annotated RNA families. Unfortunately, searching for new family members using covariance models (CMs) is very time consum...

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Detalhes bibliográficos
Main Authors: Janssen, Stefan, Reeder, Jens, Giegerich, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277397/
https://ncbi.nlm.nih.gov/pubmed/18312625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-131
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