Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling

Dorsoventral patterning is regulated by a system of interacting secreted proteins involving BMP, Chordin, Xolloid and Twisted gastrulation (Tsg). We have analyzed the molecular mechanism by which Tsg regulates BMP signaling. Overexpression of Tsg mRNA in Xenopus embryos has ventralizing effects simi...

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Main Authors: Larraín, Juan, Oelgeschläger, Michael, Ketpura, Nan I., Reversade, Bruno, Zakin, Lise, De Robertis, E. M.
Format: Artigo
Jezik:Inglês
Izdano: 2001
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277371/
https://ncbi.nlm.nih.gov/pubmed/11714670
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