Rate, extent and concentration dependence of histamine-evoked Weibel–Palade body exocytosis determined from individual fusion events in human endothelial cells

The rate, concentration dependence and extent of histamine-evoked Weibel–Palade body (WPB) exocytosis were investigated with time-resolved fluorescence microscopy in cultured human umbilical vein endothelial cells expressing WPB-targeted chimeras of enhanced green fluorescent protein (EGFP). Exocyto...

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Bibliographic Details
Main Authors: Erent, M, Meli, A, Moisoi, N, Babich, V, Hannah, M J, Skehel, P, Knipe, L, Zupančič, G, Ogden, D, Carter, T
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2007
Subjects:
Cardiovascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277235/
https://ncbi.nlm.nih.gov/pubmed/17540703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.132993
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