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Ca(2+)-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides

Extracellular ATP is a potent surfactant secretagogue but its origin in the alveolus, its mechanism(s) of release and its regulatory pathways remain unknown. Previously, we showed that hypotonic swelling of alveolar A549 cells induces Ca(2+)-dependent secretion of several adenosine and uridine nucle...

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Detalles Bibliográficos
Main Authors: Tatur, Sabina, Groulx, Nicolas, Orlov, Sergei N, Grygorczyk, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277166/
https://ncbi.nlm.nih.gov/pubmed/17702822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.133314
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